Buy AB-Chminaca Jual
Uncover the Realm of AB-Chminaca: A Leading Designer Drug
Buy AB-Chminaca Jual Embark on a journey into the world of AB-Chminaca, a designer drug initially recognized in synthetic cannabis blends in Japan back in 2013. By 2018, it had secured its place as the third most prevalent synthetic cannabinoid discovered in substances seized by the vigilant Drug Enforcement Agency.
The (S)-Enantiomer: A Potent Agonist
Delve into the intricacies of AB-Chminaca with the spotlight on its (S)-enantiomer, as outlined in a 2009 Pfizer patent. This specific enantiomer has been recognized as a formidable agonist of the CB1 and CB2 receptors, showcasing EC50 values of 1.2 nM and 3.5 nM, respectively. Notably, AB-Chminaca is a result of deliberate drug design, sharing a resemblance to AB-FUBINACA but distinguished by the substitution of the isopropyl group with a tert-butyl group.
Analogues and Advancements
Witness the evolution within the designer drug landscape with the emergence of an analogue named ADSB-FUB-187. This variant features a more functionally advanced carboxamide substituent, underlining the constant exploration and innovation within this domain.
Technical Insight
For those diving into the technicalities, AB-Chminaca is formally identified as N-[1-(aminocarbonyl)-2,2-dimethylpropyl]-1-[(4-fluorophenyl)methyl]-1H-indazole-3-carboxamide. Its molecular formula, C21H23FN4O2, and purity exceeding 98% reinforce its precise composition. This neat solid formulation assures stability over three years when stored at -20°C.
Legality and Metabolism
Navigate the legal landscape as AB-Chminaca falls under the classification of a Schedule I controlled substance in the United States. The intricate metabolism of this compound reveals pathways involving alkyl and indazole hydroxylation, terminal amide hydrolysis, subsequent glucuronide conjugations, and dehydrogenation.
Cautionary Tales
While the exploration of AB-Chminaca unveils its potential, caution is paramount. One recorded case links it to death through coronary arterial thrombosis. Additionally, at least eight deaths in Hungary in 2015, all involving individuals below 21, are associated with the usage of this material, emphasizing the need for responsible use.
Warning: This product is not intended for human or veterinary use. Buy AB-Chminaca Jual responsibly.
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